Department Calendar of Events

Many chronic diseases are now believed to be due to a combination of an individual’s genome and their cumulative environmental exposure. Exposome, analogous to genome, is a bold
conceptual leap, seeking to bridge the roles of the environment and genome in human disease. The University of Toronto just signed a tripartite agreement with Utrecht University and the
Chinese University of Hong Kong; a focus will be collaboration on exposomics research. This event will serve as UofT’s launch for this initiative. The talks will introduce the exposome,
identify related research needs and challenges, and provide ongoing and proposed initiatives in Canada and abroad.

Moderator: Paul Demers, Cancer Care Ontario and DLSPH

Seminar speaker: Dr. Roel Vermeulen, Utrecht University

Panel members:

• Dr. Howard Hu, Dean, DLSPH
• Dr. Jeff Brook, Environment and Climate Change Canada and DLSPH
• Dr. Greg Evans, Chemical Engineering and Applied Chemistry and DLSPH

Dr. Shawn C. Owen from the University of Utah’s Department of Pharmaceutical Chemistry will be giving a talk entitled, Building superior biologics: Enhancing ADCs, resurrecting ADEPT and replacing ELISA. The talk will take place in the Rosebrugh Building, Room 208 from 1-2pm on Tuesday, May 24. For more information, click here.

Exclusive to ChemE alumni from the honoured class years. A nice casual lunch will be served in the undergrad common room (WB238) with tours of ChemE labs to follow. To register visit, springreunion.utoronto.ca

BioZone and the Faculty of Applied Science & Engineering are very pleased to be able to invite you to an Open House that will showcase the services available at the BioZone Mass Spectrometry Facility. The Mass Spectrometry Facility operates at the University of Toronto in the Department of Chemical Engineering & Applied Chemistry and offers proteomics, metabolomics, and small molecule analysis, as well as method development services and expert advice on these techniques.

The purpose of this event is to promote discussion on the potential uses of mass spectrometry in order to solve complex research questions and to promote the development of novel and relevant mass spectrometry protocols.

Registration required. To register, visit https://www.eventbrite.ca/e/biozone-mass-spectrometry-facility-open-house-tickets-25705854904

At the Open House you will learn about:

• Exciting new developments in mass spectrometry-based proteomics, small molecule analysis and metabolomics;
• How mass spectrometry can support research and product development;
• The types of analysis supported at the BioZone Mass Spectrometry Facility;
• Starting material requirements, sample preparation, and protocol development.

Agenda:

• 09:00 – Keynote: Decoding metabolic evolution by high-resolution mass spectrometry – Professor Ian Lewis
• 09:45 – Capabilities and use of BioZone Mass Spec
• 10:15 – Case studies 1 (Professor Arthur Chan and More)
• 10:45 – Break
• 11:00 – Case Studies 2 (Professor Adam Rosebrock and more)
• 11:45 – Open Discussion
• 12:30 – Tour
• 12:45 – Lunch and Networking

Keynote:

Decoding metabolic evolution by high-resolution mass spectrometry
The fundamental nutritional requirements of cells are common to almost all living organisms. However, evolutionary pressures have radically diversified the strategies organisms use to meet these demands. One of the most extreme contrasts in nutritional strategies can be found in host-pathogen metabolic exchanges. Host organisms supply a predictable supply of nutrients to their cells despite dietary diversity, unpredictable energy output, and famine. Pathogens, by contrast, avoid nutritional adversity by stealing from their host. The nutrients pathogens come to rely on, and their strategies for acquiring these molecules, have a direct bearing on the severity and clinical presentation of infections. The Lewis laboratory specializes in unraveling these complex host/pathogen metabolic interactions using high-resolution mass spectrometry and multidimensional nuclear magnetic resonance spectroscopy. I will discuss the unique challenges one must overcome when unravelling these complex multi-organism metabolic systems and describe how the unique metabolic selective forces have shaped the evolution of human pathogens.

2016-2017 Lectures at the Leading Edge

Bioconversion of Methane by Anaerobic Methanotrophic Bacteria

Mary Lidstrom, University of Washington

2016-2017 Irving O. Shoichet Distinguished Lecture

Regenerative Engineering: Convergence in Action

Cato Laurencin, University of Connecticut

2016-2017 Lectures at the Leading Edge

Extreme Transitions of Flow Properties: Gas Hydrate Jamming and Discontinuous Shear Thickening

Jeffrey Morris, City College of New York

2016-2017 Lectures at the Leading Edge

Helping Nanomaterials Reach Their Colloidal Potential

Keith Johnston, University of Texas

2016-2017 Lectures at the Leading Edge

Teaching Learning by Learning Teaching: What I’ve Learned and Wish I’d Known

Greg Evans, University of Toronto